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Open Access Open Badges Commentary

Cancer biomarkers and targeted therapies

Zhiyuan Shen

Author Affiliations

The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, 195 Little Albany Street, New Brunswick, NJ 08903, USA

Cell & Bioscience 2013, 3:6  doi:10.1186/2045-3701-3-6

Published: 6 February 2013

First paragraph (this article has no abstract)

Cancer is a disease that showcases great molecular diversity among many individuals. Patients with the same clinically diagnosed cancer often vary in their response to the same treatment because each case of cancer has a unique molecular signature and pathological evolution. Therefore, individualized therapy is paramount for improving of cancer treatment. The development of rationalized and individualized therapy is reliant on the identification of the specific biomarkers, validation of the biomarkers to identify the therapeutic targets, and drug development against the identified targets.