MSCs have a tropism for tumors. We have demonstrated that inflammatory cytokines could effectively induce immunosuppression of MSCs. Our results suggest that the MSCs in tumor inflammatory microenvironment may be elicited of immunosuppressive function, which will help tumor to escape from the immunity surveillance.
Han et al. Cell & Bioscience 2012 2:8 doi:10.1186/2045-3701-2-8